Safety and Efficacy of Tocilizumab for the Treatment of Rheumatoid Arthritis

Because of the pathological role of IL-6 in rheumatoid arthritis (RA), tocilizumab (TCZ), a humanized anti-IL-6 receptor monoclonal antibody, was expected to improve inflammation and joint destruction of RA. Indeed, randomized clinical trials demonstrated the clinical efficacy of TCZ as monotherapy...

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Bibliografske podrobnosti
Main Authors: Ogata, Atsushi, Hirano, Toru, Hishitani, Yoshihiro, Tanaka, Toshio
Format: Artigo
Jezik:Inglês
Izdano: Libertas Academica 2012
Teme:
Expert Review
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3306224/
https://ncbi.nlm.nih.gov/pubmed/22438671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4137/CMAMD.S7371
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