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Baseline metabolic profiles of early rheumatoid arthritis patients achieving sustained drug-free remission after initiating treat-to-target tocilizumab, methotrexate, or the combination: insights from systems biology

BACKGROUND: We previously identified, in newly diagnosed rheumatoid arthritis (RA) patients, networks of co-expressed genes and proteomic biomarkers associated with achieving sustained drug-free remission (sDFR) after treatment with tocilizumab- or methotrexate-based strategies. The aim of this stud...

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Detalhes bibliográficos
Publicado no:Arthritis Res Ther
Main Authors: Teitsma, Xavier M, Yang, Wei, Jacobs, Johannes W G, Pethö-Schramm, Attila, Borm, Michelle E A, Harms, Amy C, Hankemeier, Thomas, van Laar, Jacob M, Bijlsma, Johannes W J, Lafeber, Floris P J G
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6235217/
https://ncbi.nlm.nih.gov/pubmed/30322408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-018-1729-2
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