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Anti-CD48 mAb attenuates experimental autoimmune encephalomyelitis by limiting the number of pathogenic CD4+ T cells()

CD48 (SLAMF2) is an adhesion and costimulatory molecule constitutively expressed on hematopoietic cells. Polymorphisms in CD48 have been linked to susceptibility to multiple sclerosis (MS), and altered expression of the structurally related protein CD58 (LFA-3) is associated with disease remission i...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: McArdel, Shannon L., Brown, Daniel R., Sobel, Raymond A., Sharpe, Arlene H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5356934/
https://ncbi.nlm.nih.gov/pubmed/27581174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1600706
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