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Anti-CD48 mAb attenuates experimental autoimmune encephalomyelitis by limiting the number of pathogenic CD4+ T cells()

CD48 (SLAMF2) is an adhesion and costimulatory molecule constitutively expressed on hematopoietic cells. Polymorphisms in CD48 have been linked to susceptibility to multiple sclerosis (MS), and altered expression of the structurally related protein CD58 (LFA-3) is associated with disease remission i...

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Библиографические подробности
Опубликовано в: :J Immunol
Главные авторы: McArdel, Shannon L., Brown, Daniel R., Sobel, Raymond A., Sharpe, Arlene H.
Формат: Artigo
Язык:Inglês
Опубликовано: 2016
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5356934/
https://ncbi.nlm.nih.gov/pubmed/27581174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1600706
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