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Evolutionary gain of alanine mischarging to non-cognate tRNAs with a G4:U69 base pair
Fidelity of translation, which is predominately dictated by the accuracy of aminoacyl-tRNA synthetases in pairing amino acids with correct tRNAs, is of central importance in biology. Yet, deliberate modifications of translational fidelity can be beneficial. Here we found human and not E. coli AlaRS...
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| 出版年: | J Am Chem Soc |
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| 主要な著者: | , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2016
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5356932/ https://ncbi.nlm.nih.gov/pubmed/27622773 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.6b07121 |
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