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SAHA and/or MG132 reverse the aggressive phenotypes of glioma cells: An in vitro and vivo study

To elucidate the anti-tumor effects and molecular mechanisms of SAHA (a histone deacetylase inhibitor) and MG132 (a proteasome inhibitor) on the aggressive phenotypes of glioma cells, we treated U87 and U251 cells with SAHA or/and MG132, and detected phenotypes’ assays with phenotype-related molecul...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Yang, Xue-feng, Zhao, Zhi-juan, Liu, Jia-jie, Yang, Xiang-hong, Gao, Yang, Zhao, Shuang, Shi, Shuai, Huang, Ke-qiang, Zheng, Hua-chuan
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5356872/
https://ncbi.nlm.nih.gov/pubmed/27911270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13680
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