The in vitro and in vivo effects of nuclear and cytosolic parafibromin expression on the aggressive phenotypes of colorectal cancer cells: a search of potential gene therapy target

Down-regulated parafibromin is positively linked to the pathogenesis of parathyroid, lung, breast, ovarian, gastric and colorectal cancers. Here, we found that wild-type (WT) parafibromin overexpression suppressed proliferation, tumor growth, induced cell cycle arrest and apoptosis in colorectal can...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Oncotarget
Autori principali: Zheng, Hua-chuan, Liu, Jia-jie, Li, Jing, Wu, Ji-cheng, Yang, Lei, Zhao, Gui-feng, Zhao, Xin, Jiang, Hua-mao, Huang, Ke-qiang, Li, Zhi-jie
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2017
Soggetti:
Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5410330/
https://ncbi.nlm.nih.gov/pubmed/28223542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.15377
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