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Changes in the methylation status of the Oct3/4, Nanog, and Sox2 promoters in stem cells during regeneration of rat tracheal epithelium after injury

We investigated the relationship between promoter methylation and tracheal stem cell activation. We developed a model of rat tracheal epithelium regeneration after 5-fluorouracil (5-FU)-induced injury. Using immunohistochemistry and Western blotting, the expression levels of the stem cell pluripoten...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Zhou, Ying, Song, Nan, Li, Xin, Han, Ying, Ren, Zihan, Xu, Jing-xian, Han, Yu-chen, Li, Fang, Jia, Xinshan
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5356857/
https://ncbi.nlm.nih.gov/pubmed/27935870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13818
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