Characterization of SOX2, OCT4 and NANOG in Ovarian Cancer Tumor-Initiating Cells

SIMPLE SUMMARY: SOX2, OCT4, and NANOG are enriched in ovarian cancer spheroids and correlate with tumor-initiating cell markers, CD117 and ALDH/CD133. SOX2, relative to OCT4 or NANOG, is a stronger indictor of chemoresistance, tumor-initiation, and recurrent disease. Including SOX2 in evaluation of...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Robinson, Mikella, Gilbert, Samuel F., Waters, Jennifer A., Lujano-Olazaba, Omar, Lara, Jacqueline, Alexander, Logan J., Green, Samuel E., Burkeen, Gregory A., Patrus, Omid, Sarwar, Zinia, Holmberg, Ryne, Wang, Christine, House, Carrie D.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7828139/
https://ncbi.nlm.nih.gov/pubmed/33445692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13020262
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