Genetic and epigenetic characterization of the BRCA1 gene in Brazilian women at-risk for hereditary breast cancer

This study aimed to characterize women at-risk for hereditary BC regarding their clinical and molecular characteristics (mutation and methylation in the BRCA1 gene) and correlate the gene expression levels with histopathological, clinical and family history information. BRCA1 real time qPCR was perf...

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Bibliografiske detaljer
Udgivet i:Oncotarget
Main Authors: Felicio, Paula Silva, Melendez, Matias Eliseo, Arantes, Lidia Maria Rebolho Batista, Kerr, Ligia Maria, Carraro, Dirce Maria, Grasel, Rebeca Silveira, Campacci, Natalia, Scapulatempo-Neto, Cristovam, Fernandes, Gabriela Carvalho, de Carolina, Ana Carvalho, Palmero, Edenir Inêz
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2016
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5356847/
https://ncbi.nlm.nih.gov/pubmed/27926510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13750
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