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Association of polymorphisms with a family history of cancer and the presence of germline mutations in the BRCA1/BRCA2 genes

INTRODUCTION: Breast cancer (BC) is an important public health problem worldwide. In Brazil, breast cancer is the most frequently diagnosed tumor and the leading cause of cancer death in women. Hereditary cancer represents approximately 5 to 10 % of BC cases. Even outside the hereditary cancer conte...

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Detalhes bibliográficos
Publicado no:Hered Cancer Clin Pract
Main Authors: Fernandes, Gabriela C., Michelli, Rodrigo A. D., Scapulatempo-Neto, Cristovam, Palmero, Edenir I.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4712611/
https://ncbi.nlm.nih.gov/pubmed/26770289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13053-015-0042-1
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