Association of polymorphisms with a family history of cancer and the presence of germline mutations in the BRCA1/BRCA2 genes

INTRODUCTION: Breast cancer (BC) is an important public health problem worldwide. In Brazil, breast cancer is the most frequently diagnosed tumor and the leading cause of cancer death in women. Hereditary cancer represents approximately 5 to 10 % of BC cases. Even outside the hereditary cancer conte...

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Enregistré dans:
Détails bibliographiques
Publié dans:Hered Cancer Clin Pract
Auteurs principaux: Fernandes, Gabriela C., Michelli, Rodrigo A. D., Scapulatempo-Neto, Cristovam, Palmero, Edenir I.
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2016
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4712611/
https://ncbi.nlm.nih.gov/pubmed/26770289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13053-015-0042-1
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