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Influence of a fluorobenzene nucleobase analogue on the conformational flexibility of RNA studied by molecular dynamics simulations

Chemically modified bases are frequently used to stabilize nucleic acids, to study the driving forces for nucleic acid structure formation and to tune DNA and RNA hybridization conditions. In particular, fluorobenzene and fluorobenzimidazole base analogues can act as universal bases able to pair wit...

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Detalhes bibliográficos
Main Authors: Zacharias, Martin, Engels, Joachim W.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC535679/
https://ncbi.nlm.nih.gov/pubmed/15576356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkh971
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