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Influence of a fluorobenzene nucleobase analogue on the conformational flexibility of RNA studied by molecular dynamics simulations

Chemically modified bases are frequently used to stabilize nucleic acids, to study the driving forces for nucleic acid structure formation and to tune DNA and RNA hybridization conditions. In particular, fluorobenzene and fluorobenzimidazole base analogues can act as universal bases able to pair wit...

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Hlavní autoři: Zacharias, Martin, Engels, Joachim W.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2004
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC535679/
https://ncbi.nlm.nih.gov/pubmed/15576356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkh971
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