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Sorafenib pretreatment enhances radiotherapy through targeting MEK/ERK/NF-κB pathway in human hepatocellular carcinoma-bearing mouse model

Patients with unresectable hepatocellular carcinoma (HCC) usually have poor prognosis because current monotherapy including surgery, chemotherapy and radiotherapy (RT) are not effective. Combination therapy may be effective to overcome this clinical problem. Here, we proposed the combination of sora...

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Bibliographic Details
Published in:Oncotarget
Main Authors: Chen, John Chun-Hao, Chuang, Hui-Yen, Hsu, Fei-Ting, Chen, Yi-Chen, Chien, Yi-Chun, Hwang, Jeng-Jong
Format: Artigo
Language:Inglês
Published: Impact Journals LLC 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5356748/
https://ncbi.nlm.nih.gov/pubmed/27863427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13398
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