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Sorafenib pretreatment enhances radiotherapy through targeting MEK/ERK/NF-κB pathway in human hepatocellular carcinoma-bearing mouse model

Patients with unresectable hepatocellular carcinoma (HCC) usually have poor prognosis because current monotherapy including surgery, chemotherapy and radiotherapy (RT) are not effective. Combination therapy may be effective to overcome this clinical problem. Here, we proposed the combination of sora...

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Dades bibliogràfiques
Publicat a:Oncotarget
Autors principals: Chen, John Chun-Hao, Chuang, Hui-Yen, Hsu, Fei-Ting, Chen, Yi-Chen, Chien, Yi-Chun, Hwang, Jeng-Jong
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5356748/
https://ncbi.nlm.nih.gov/pubmed/27863427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13398
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