Sorafenib pretreatment enhances radiotherapy through targeting MEK/ERK/NF-κB pathway in human hepatocellular carcinoma-bearing mouse model

Patients with unresectable hepatocellular carcinoma (HCC) usually have poor prognosis because current monotherapy including surgery, chemotherapy and radiotherapy (RT) are not effective. Combination therapy may be effective to overcome this clinical problem. Here, we proposed the combination of sora...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Chen, John Chun-Hao, Chuang, Hui-Yen, Hsu, Fei-Ting, Chen, Yi-Chen, Chien, Yi-Chun, Hwang, Jeng-Jong
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5356748/
https://ncbi.nlm.nih.gov/pubmed/27863427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13398
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