Induction of mitochondria-mediated apoptosis and PI3K/Akt/ mTOR-mediated autophagy by aflatoxin B(2) in hepatocytes of broilers

Aflatoxins have been shown to induce hepatotoxicity in animal models, but the effects of aflatoxin B(2) (AFB(2)) on broiler hepatocytes is unclear. This study aimed to investigate the effects of AFB(2) on apoptosis and autophagy to provide an experimental basis for understanding the mechanism of afl...

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Dades bibliogràfiques
Publicat a:Oncotarget
Autors principals: Chen, Binlong, Li, Diyan, Li, Miao, Li, Sichen, Peng, Kenan, Shi, Xian, Zhou, Lanyun, Zhang, Pu, Xu, Zhongxian, Yin, Huadong, Wang, Yan, Zhao, Xiaoling, Zhu, Qing
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2016
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5356714/
https://ncbi.nlm.nih.gov/pubmed/27863407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13356
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