Unraveling the expression of the oncogene YAP1, a Wnt/beta-catenin target, in adrenocortical tumors and its association with poor outcome in pediatric patients

BACKGROUND: Overexpression of the oncogene yes-associated-protein-1 (YAP1) is associated with increased cell proliferation in human cancers. YAP1 is a potential target of the Wnt/beta-catenin pathway, which plays an important role in adrenocortical tumors (ACT). The role of YAP1 in adrenocortical tu...

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Bibliografski detalji
Izdano u:Oncotarget
Glavni autori: Abduch, Rafael H., Bueno, Ana Carolina, Leal, Leticia F., Cavalcanti, Marcelo M., Gomes, Débora C., Brandalise, Silvia R., Masterallo, Maria J., Yunes, José A., Martinelli, Carlos E., Tone, Luiz G., Tucci, Silvio, Molina, Carlos A.F., Ramalho, Fernando S., Moreira, Ayrton C., Cardinalli, Izilda A., Scrideli, Carlos A., Ramalho, Leandra N.Z., de Castro, Margaret, Antonini, Sonir R.
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2016
Teme:
Research Paper
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5356687/
https://ncbi.nlm.nih.gov/pubmed/27705928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.12382
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