Activation of HERV-K Env protein is essential for tumorigenesis and metastasis of breast cancer cells

Human endogenous retrovirus type K (HERV-K) Env protein was previously demonstrated to be overexpressed in human breast cancer (BC) cells and tissues. However, the molecular pathways driving the specific alterations are unknown. We now show that knockdown of its expression with an shRNA (shRNAenv) b...

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Опубликовано в: :Oncotarget
Главные авторы: Zhou, Fuling, Li, Ming, Wei, Yongchang, Lin, Kevin, Lu, Yue, Shen, Jianjun, Johanning, Gary L., Wang-Johanning, Feng
Формат: Artigo
Язык:Inglês
Опубликовано: Impact Journals LLC 2016
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Research Paper
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5356647/
https://ncbi.nlm.nih.gov/pubmed/27557521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11455
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