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Down-regulation of human endogenous retrovirus type K (HERV-K) viral env RNA in pancreatic cancer cells decreases cell proliferation and tumor growth
PURPOSE: We investigated the role of the human endogenous retrovirus type K (HERV-K) envelope (env) gene in pancreatic cancer (PC). EXPERIMENTAL DESIGN: shRNA was employed to knockdown (KD) the expression of HERV-K in PC cells. RESULTS: HERV-K env expression was detected in seven PC cell lines and i...
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| Опубликовано в: : | Clin Cancer Res |
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| Главные авторы: | , , , , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2017
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5777511/ https://ncbi.nlm.nih.gov/pubmed/28679769 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-17-0001 |
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