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Activation of HERV-K Env protein is essential for tumorigenesis and metastasis of breast cancer cells

Human endogenous retrovirus type K (HERV-K) Env protein was previously demonstrated to be overexpressed in human breast cancer (BC) cells and tissues. However, the molecular pathways driving the specific alterations are unknown. We now show that knockdown of its expression with an shRNA (shRNAenv) b...

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Dades bibliogràfiques
Publicat a:Oncotarget
Autors principals: Zhou, Fuling, Li, Ming, Wei, Yongchang, Lin, Kevin, Lu, Yue, Shen, Jianjun, Johanning, Gary L., Wang-Johanning, Feng
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5356647/
https://ncbi.nlm.nih.gov/pubmed/27557521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11455
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