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Electron transfer in DNA duplexes containing 2-methyl-1,4-naphthoquinone
2-Methyl-1,4-naphthoquinone (menadione, MQ) was linked to synthetic oligonucleotides and exposed to near-UV light to generate base radical cations in DNA. This model system of electron transfer induced alkali-labile breaks at GG doublets, similar to anthraquinone and metallointercalators systems. In...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC535664/ https://ncbi.nlm.nih.gov/pubmed/15585661 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkh950 |
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