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Chenodeoxycholic acid activates NLRP3 inflammasome and contributes to cholestatic liver fibrosis
Accumulation of hydrophobic bile acids in the liver contributes to cholestatic liver injury. Inflammation induced by excessive bile acids is believed to play a crucial role, however, the mechanisms of bile acids triggered inflammatory response remain unclear. Recent studies have highlighted the effe...
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| 出版年: | Oncotarget |
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| 主要な著者: | , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Impact Journals LLC
2016
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5356637/ https://ncbi.nlm.nih.gov/pubmed/27924062 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13796 |
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