Deoxycholic Acid-Mediated Sphingosine-1-Phosphate Receptor 2 Signaling Exacerbates DSS-Induced Colitis through Promoting Cathepsin B Release

We recently have proved that excessive fecal DCA caused by high-fat diet may serve as an endogenous danger-associated molecular pattern to activate NLRP3 inflammasome and thus contributes to the development of inflammatory bowel disease (IBD). Moreover, the effect of DCA on inflammasome activation i...

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Publicado en:J Immunol Res
Autores principales: Zhao, Shengnan, Gong, Zizhen, Du, Xixi, Tian, Chunyan, Wang, Lingyu, Zhou, Jiefei, Xu, Congfeng, Chen, Yingwei, Cai, Wei, Wu, Jin
Formato: Artigo
Lenguaje:Inglês
Publicado: Hindawi 2018
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5966668/
https://ncbi.nlm.nih.gov/pubmed/29854830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/2481418
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