Phenotypic screening reveals TNFR2 as a promising target for cancer immunotherapy

Antibodies that target cell-surface molecules on T cells can enhance anti-tumor immune responses, resulting in sustained immune-mediated control of cancer. We set out to find new cancer immunotherapy targets by phenotypic screening on human regulatory T (Treg) cells and report the discovery of novel...

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Publicat a:Oncotarget
Autors principals: Williams, Geoffrey S., Mistry, Bina, Guillard, Sandrine, Ulrichsen, Jane Coates, Sandercock, Alan M., Wang, Jun, González-Muñoz, Andrea, Parmentier, Julie, Black, Chelsea, Soden, Jo, Freeth, Jim, Jovanović, Jelena, Leyland, Rebecca, Al-Lamki, Rafia S., Leishman, Andrew J., Rust, Steven J., Stewart, Ross, Jermutus, Lutz, Bradley, John R., Bedian, Vahe, Valge-Archer, Viia, Minter, Ralph, Wilkinson, Robert W.
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2016
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5356554/
https://ncbi.nlm.nih.gov/pubmed/27626702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11943
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