Interferon-stimulated gene of 20 kDa protein (ISG20) degrades RNA of hepatitis B virus to impede the replication of HBV in vitro and in vivo

Hepatitis B virus (HBV) barely induces host interferon (IFN)-stimulated genes (ISGs), which allows efficient HBV replication in the immortalized mouse hepatocytes as per human hepatocytes. Here we found that transfection of Isg20 plasmid robustly inhibits the HBV replication in HBV-infected hepatocy...

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Dades bibliogràfiques
Publicat a:Oncotarget
Autors principals: Leong, Chean Ring, Funami, Kenji, Oshiumi, Hiroyuki, Mengao, Deng, Takaki, Hiromi, Matsumoto, Misako, Aly, Hussein H., Watashi, Koichi, Chayama, Kazuaki, Seya, Tsukasa
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2016
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5356548/
https://ncbi.nlm.nih.gov/pubmed/27626689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11907
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