Interferon-stimulated gene of 20 kDa protein (ISG20) degrades RNA of hepatitis B virus to impede the replication of HBV in vitro and in vivo

Hepatitis B virus (HBV) barely induces host interferon (IFN)-stimulated genes (ISGs), which allows efficient HBV replication in the immortalized mouse hepatocytes as per human hepatocytes. Here we found that transfection of Isg20 plasmid robustly inhibits the HBV replication in HBV-infected hepatocy...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Leong, Chean Ring, Funami, Kenji, Oshiumi, Hiroyuki, Mengao, Deng, Takaki, Hiromi, Matsumoto, Misako, Aly, Hussein H., Watashi, Koichi, Chayama, Kazuaki, Seya, Tsukasa
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5356548/
https://ncbi.nlm.nih.gov/pubmed/27626689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11907
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