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Synthesis and Evaluation of Paclitaxel-Loaded Gold Nanoparticles for Tumor-Targeted Drug Delivery

The synthesis of a series of thiolated paclitaxel analogs is described as part of a novel nanomedicine program aimed at developing formulations of paclitaxel that will bind to gold nanoparticles for tumor targeted drug delivery. Preliminary evaluation of the new nanomedicine comprised of 27 nm gold...

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Bibliografske podrobnosti
izdano v:Bioconjug Chem
Main Authors: Paciotti, Giulio F., Zhao, Jielu, Cao, Shugeng, Brodie, Peggy J., Tamarkin, Lawrence, Huhta, Marja, Myer, Lonnie D., Friedman, Jay, Kingston, David G. I.
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5356508/
https://ncbi.nlm.nih.gov/pubmed/27689882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.bioconjchem.6b00405
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