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Synthesis and Evaluation of Paclitaxel-Loaded Gold Nanoparticles for Tumor-Targeted Drug Delivery

The synthesis of a series of thiolated paclitaxel analogs is described as part of a novel nanomedicine program aimed at developing formulations of paclitaxel that will bind to gold nanoparticles for tumor targeted drug delivery. Preliminary evaluation of the new nanomedicine comprised of 27 nm gold...

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Detalles Bibliográficos
Publicado en:Bioconjug Chem
Autores principales: Paciotti, Giulio F., Zhao, Jielu, Cao, Shugeng, Brodie, Peggy J., Tamarkin, Lawrence, Huhta, Marja, Myer, Lonnie D., Friedman, Jay, Kingston, David G. I.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5356508/
https://ncbi.nlm.nih.gov/pubmed/27689882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.bioconjchem.6b00405
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