Ex vivo drug response profiling detects recurrent sensitivity patterns in drug-resistant acute lymphoblastic leukemia

Drug sensitivity and resistance testing on diagnostic leukemia samples should provide important functional information to guide actionable target and biomarker discovery. We provide proof of concept data by profiling 60 drugs on 68 acute lymphoblastic leukemia (ALL) samples mostly from resistant dis...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Frismantas, Viktoras, Dobay, Maria Pamela, Rinaldi, Anna, Tchinda, Joelle, Dunn, Samuel H., Kunz, Joachim, Richter-Pechanska, Paulina, Marovca, Blerim, Pail, Orrin, Jenni, Silvia, Diaz-Flores, Ernesto, Chang, Bill H., Brown, Timothy J., Collins, Robert H., Uhrig, Sebastian, Balasubramanian, Gnana P., Bandapalli, Obul R., Higi, Salome, Eugster, Sabrina, Voegeli, Pamela, Delorenzi, Mauro, Cario, Gunnar, Loh, Mignon L., Schrappe, Martin, Stanulla, Martin, Kulozik, Andreas E., Muckenthaler, Martina U., Saha, Vaskar, Irving, Julie A., Meisel, Roland, Radimerski, Thomas, Von Stackelberg, Arend, Eckert, Cornelia, Tyner, Jeffrey W., Horvath, Peter, Bornhauser, Beat C., Bourquin, Jean-Pierre
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2017
Assuntos:
Lymphoid Neoplasia
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5356455/
https://ncbi.nlm.nih.gov/pubmed/28122742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2016-09-738070
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