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Extracellular Hsp90 and TGFβ regulate adhesion, migration and anchorage independent growth in a paired colon cancer cell line model

BACKGROUND: Tumour metastasis remains the major cause of death in cancer patients and, to date, the mechanism and signalling pathways governing this process are not completely understood. The TGF-β pathway is the most commonly mutated pathway in cancer, however its role in cancer progression is cont...

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Publicado en:BMC Cancer
Autores principales: de la Mare, Jo-Anne, Jurgens, Tamarin, Edkins, Adrienne L.
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5356307/
https://ncbi.nlm.nih.gov/pubmed/28302086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-017-3190-z
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