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Inhibitor Discovery for the Human GLUT1 from Homology Modeling and Virtual Screening

The human Glucose Transporter 1 (hGLUT1 or SLC2A1) is a facilitative membrane transporter found in the liver, intestines, kidney, and brain, where it transports sugars such as D-glucose and D-galactose. Genetic variations in hGLUT1 are associated with a broad range of diseases and metabolic disorder...

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Detalhes bibliográficos
Publicado no:ACS Chem Biol
Main Authors: Ung, Peter Man-Un, Song, Wenxin, Cheng, Lili, Zhao, Xinbin, Hu, Hailin, Chen, Ligong, Schlessinger, Avner
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5356226/
https://ncbi.nlm.nih.gov/pubmed/27128978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.6b00304
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