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The metabolic waste ammonium regulates mTORC2 and mTORC1 signaling
Two structurally and functionally distinct mammalian TOR complexes control cell growth and metabolism in physiological and pathological contexts including cancer. Upregulated glutaminolysis is part of the metabolic reprogramming occurring in cancer, providing fuels for growth but also liberating amm...
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| Veröffentlicht in: | Sci Rep |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5355986/ https://ncbi.nlm.nih.gov/pubmed/28303961 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep44602 |
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