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The metabolic waste ammonium regulates mTORC2 and mTORC1 signaling
Two structurally and functionally distinct mammalian TOR complexes control cell growth and metabolism in physiological and pathological contexts including cancer. Upregulated glutaminolysis is part of the metabolic reprogramming occurring in cancer, providing fuels for growth but also liberating amm...
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| Pubblicato in: | Sci Rep |
|---|---|
| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5355986/ https://ncbi.nlm.nih.gov/pubmed/28303961 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep44602 |
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