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Pre-plaque conformational changes in Alzheimer's disease-linked Aβ and APP
Reducing levels of the aggregation-prone Aβ peptide that accumulates in the brain with Alzheimer's disease (AD) has been a major target of experimental therapies. An alternative approach may be to stabilize the physiological conformation of Aβ. To date, the physiological state of Aβ in brain re...
Enregistré dans:
| Publié dans: | Nat Commun |
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| Auteurs principaux: | , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group
2017
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5355803/ https://ncbi.nlm.nih.gov/pubmed/28287086 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms14726 |
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