An All-Recombinant Protein-Based Culture System Specifically Identifies Hematopoietic Stem Cell Maintenance Factors

Hematopoietic stem cells (HSCs) are considered one of the most promising therapeutic targets for the treatment of various blood disorders. However, due to difficulties in establishing stable maintenance and expansion of HSCs in vitro, their insufficient supply is a major constraint to transplantatio...

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Veröffentlicht in:Stem Cell Reports
Hauptverfasser: Ieyasu, Aki, Ishida, Reiko, Kimura, Takaharu, Morita, Maiko, Wilkinson, Adam C., Sudo, Kazuhiro, Nishimura, Toshinobu, Ohehara, Jun, Tajima, Yoko, Lai, Chen-Yi, Otsu, Makoto, Nakamura, Yukio, Ema, Hideo, Nakauchi, Hiromitsu, Yamazaki, Satoshi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2017
Schlagworte:
Report
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5355634/
https://ncbi.nlm.nih.gov/pubmed/28238792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2017.01.015
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