An All-Recombinant Protein-Based Culture System Specifically Identifies Hematopoietic Stem Cell Maintenance Factors

Hematopoietic stem cells (HSCs) are considered one of the most promising therapeutic targets for the treatment of various blood disorders. However, due to difficulties in establishing stable maintenance and expansion of HSCs in vitro, their insufficient supply is a major constraint to transplantatio...

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Bibliographic Details
Published in:Stem Cell Reports
Main Authors: Ieyasu, Aki, Ishida, Reiko, Kimura, Takaharu, Morita, Maiko, Wilkinson, Adam C., Sudo, Kazuhiro, Nishimura, Toshinobu, Ohehara, Jun, Tajima, Yoko, Lai, Chen-Yi, Otsu, Makoto, Nakamura, Yukio, Ema, Hideo, Nakauchi, Hiromitsu, Yamazaki, Satoshi
Format: Artigo
Language:Inglês
Published: Elsevier 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5355634/
https://ncbi.nlm.nih.gov/pubmed/28238792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2017.01.015
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