Age-Associated Characteristics of Murine Hematopoietic Stem Cells

Little is known of age-associated functional changes in hematopoietic stem cells (HSCs). We studied aging HSCs at the clonal level by isolating CD34(−/low)c-Kit(+)Sca-1(+) lineage marker–negative (CD34(−)KSL) cells from the bone marrow of C57BL/6 mice. A population of CD34(−)KSL cells gradually expa...

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Bibliografiska uppgifter
Huvudupphovsmän: Sudo, Kazuhiro, Ema, Hideo, Morita, Yohei, Nakauchi, Hiromitsu
Materialtyp: Artigo
Språk:Inglês
Publicerad: The Rockefeller University Press 2000
Ämnen:
Original Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2193349/
https://ncbi.nlm.nih.gov/pubmed/11067876
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