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Heterogeneity and hierarchy within the most primitive hematopoietic stem cell compartment

Hematopoietic stem cells (HSCs) have been extensively characterized based on functional definitions determined by experimental transplantation into lethally irradiated mice. In mice, HSCs are heterogeneous with regard to self-renewal potential, in vitro colony-forming activity, and in vivo behavior....

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Autors principals: Morita, Yohei, Ema, Hideo, Nakauchi, Hiromitsu
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2882827/
https://ncbi.nlm.nih.gov/pubmed/20421392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20091318
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