Hierarchical and Redundant Roles of Activating FcγRs in Protection against Influenza Disease by M2e-Specific IgG1 and IgG2a Antibodies

The ectodomain of matrix protein 2 is a universal influenza A virus vaccine candidate that provides protection through antibody-dependent effector mechanisms. Here we compared the functional engagement of Fcγ receptor (FcγR) family members by two M2e-specific monoclonal antibodies (MAbs), MAb 37 (Ig...

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Detalles Bibliográficos
Publicado en:J Virol
Main Authors: Van den Hoecke, Silvie, Ehrhardt, Katrin, Kolpe, Annasaheb, El Bakkouri, Karim, Deng, Lei, Grootaert, Hendrik, Schoonooghe, Steve, Smet, Anouk, Bentahir, Mostafa, Roose, Kenny, Schotsaert, Michael, Schepens, Bert, Callewaert, Nico, Nimmerjahn, Falk, Staeheli, Peter, Hengel, Hartmut, Saelens, Xavier
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2017
Assuntos:
Pathogenesis and Immunity
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5355615/
https://ncbi.nlm.nih.gov/pubmed/28077656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02500-16
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