Hierarchical and Redundant Roles of Activating FcγRs in Protection against Influenza Disease by M2e-Specific IgG1 and IgG2a Antibodies

The ectodomain of matrix protein 2 is a universal influenza A virus vaccine candidate that provides protection through antibody-dependent effector mechanisms. Here we compared the functional engagement of Fcγ receptor (FcγR) family members by two M2e-specific monoclonal antibodies (MAbs), MAb 37 (Ig...

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Dettagli Bibliografici
Pubblicato in:J Virol
Autori principali: Van den Hoecke, Silvie, Ehrhardt, Katrin, Kolpe, Annasaheb, El Bakkouri, Karim, Deng, Lei, Grootaert, Hendrik, Schoonooghe, Steve, Smet, Anouk, Bentahir, Mostafa, Roose, Kenny, Schotsaert, Michael, Schepens, Bert, Callewaert, Nico, Nimmerjahn, Falk, Staeheli, Peter, Hengel, Hartmut, Saelens, Xavier
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2017
Soggetti:
Pathogenesis and Immunity
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5355615/
https://ncbi.nlm.nih.gov/pubmed/28077656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02500-16
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