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The V3 Loop of HIV-1 Env Determines Viral Susceptibility to IFITM3 Impairment of Viral Infectivity

Interferon-inducible transmembrane proteins (IFITMs) inhibit a broad spectrum of viruses, including HIV-1. IFITM proteins deter HIV-1 entry when expressed in target cells and also impair HIV-1 infectivity when expressed in virus producer cells. However, little is known about how viruses resist IFITM...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Wang, Yimeng, Pan, Qinghua, Ding, Shilei, Wang, Zhen, Yu, Jingyou, Finzi, Andrés, Liu, Shan-Lu, Liang, Chen
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5355610/
https://ncbi.nlm.nih.gov/pubmed/28100616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02441-16
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