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The N-Terminal Region of IFITM3 Modulates Its Antiviral Activity by Regulating IFITM3 Cellular Localization

Interferon-inducible transmembrane (IFITM) protein family members IFITM1, -2, and -3 restrict the infection of multiple enveloped viruses. Significant enrichment of a minor IFITM3 allele was recently reported for patients who were hospitalized for seasonal and 2009 H1N1 pandemic flu. This IFITM3 all...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Jia, Rui, Pan, Qinghua, Ding, Shilei, Rong, Liwei, Liu, Shan-Lu, Geng, Yunqi, Qiao, Wentao, Liang, Chen
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3503121/
https://ncbi.nlm.nih.gov/pubmed/23055554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01828-12
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