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Multiscale Modeling of Complex Formation and CD80 Depletion during Immune Synapse Development

The mechanisms that discriminate self- and foreign antigen before T cell activation are unresolved. As part of the immune system’s adaptive response to specific infections or neoplasms, antigen-presenting cells (APC) and effector T cells form transcellular molecular complexes. CTLA4 expression on re...

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Bibliografiska uppgifter
I publikationen:Biophys J
Huvudupphovsmän: Sugár, István P., Das, Jayajit, Jayaprakash, Ciriyam, Sealfon, Stuart C.
Materialtyp: Artigo
Språk:Inglês
Publicerad: The Biophysical Society 2017
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5355541/
https://ncbi.nlm.nih.gov/pubmed/28297658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2016.12.052
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