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Evidence For Signaling From The Center Of The Immune Synapse

The role of the immune synapse, and in particular the role of the central region of the synapse (the central supramolecular activation cluster or cSMAC), is controversial. One model suggests that the sole function of the cSMAC is to downregulate receptors and turn off signaling and that TCR signalin...

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Detalhes bibliográficos
Main Authors: Čemerski, Sašo, Das, Jayajit, Giurisato, Emanuele, Markiewicz, Mary A., Allen, Paul M., Chakraborty, Arup K., Shaw, Andrey S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3962836/
https://ncbi.nlm.nih.gov/pubmed/18760640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2008.06.014
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