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The Mitogen-Activated Protein Kinase Scaffold KSR1 Is Required for Recruitment of Extracellular Signal-Regulated Kinase to the Immunological Synapse

KSR1 is a mitogen-activated protein (MAP) kinase scaffold that enhances the activation of the MAP kinase extracellular signal-regulated kinase (ERK). The function of KSR1 in NK cell function is not known. Here we show that KSR1 is required for efficient NK-mediated cytolysis and polarization of cyto...

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Detalhes bibliográficos
Main Authors: Giurisato, Emanuele, Lin, Joseph, Harding, Angus, Cerutti, Elisa, Cella, Marina, Lewis, Robert E., Colonna, Marco, Shaw, Andrey S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2648244/
https://ncbi.nlm.nih.gov/pubmed/19139278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01421-08
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