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KSR1 Modulates the Sensitivity of Mitogen-Activated Protein Kinase Pathway Activation in T Cells without Altering Fundamental System Outputs

Mitogen-activated protein kinase (MAPK) cascades are evolutionarily conserved signaling pathways that regulate cell fate decisions. They generate a wide range of signal outputs, including graded and digital responses. In T cells, MAPK activation is digital in response to T-cell-receptor stimulation;...

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Bibliografiset tiedot
Päätekijät: Lin, Joseph, Harding, Angus, Giurisato, Emanuele, Shaw, Andrey S.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology (ASM) 2009
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2663292/
https://ncbi.nlm.nih.gov/pubmed/19188442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01634-08
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