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Phosphatidylinositol 3-Kinase Activation Is Required To Form the NKG2D Immunological Synapse
The receptor NKG2D allows natural killer (NK) cells to detect virally infected, stressed, and tumor cells. In human cells, NKG2D signaling is mediated through the associated DAP10 adapter. Here we show that engagement of NKG2D by itself is sufficient to stimulate the formation of the NK immunologica...
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| Главные авторы: | , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Microbiology (ASM)
2007
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2169389/ https://ncbi.nlm.nih.gov/pubmed/17923698 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01477-07 |
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