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Evidence For Signaling From The Center Of The Immune Synapse

The role of the immune synapse, and in particular the role of the central region of the synapse (the central supramolecular activation cluster or cSMAC), is controversial. One model suggests that the sole function of the cSMAC is to downregulate receptors and turn off signaling and that TCR signalin...

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Autores principales: Čemerski, Sašo, Das, Jayajit, Giurisato, Emanuele, Markiewicz, Mary A., Allen, Paul M., Chakraborty, Arup K., Shaw, Andrey S.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2008
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3962836/
https://ncbi.nlm.nih.gov/pubmed/18760640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2008.06.014
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