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Dramatic reduction of dimensionality in large biochemical networks owing to strong pair correlations

Large multi-dimensionality of high-throughput datasets pertaining to cell signalling and gene regulation renders it difficult to extract mechanisms underlying the complex kinetics involving various biochemical compounds (e.g. proteins and lipids). Data-driven models often circumvent this difficulty...

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Autori principali: Dworkin, Michael, Mukherjee, Sayak, Jayaprakash, Ciriyam, Das, Jayajit
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Royal Society 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3385761/
https://ncbi.nlm.nih.gov/pubmed/22378749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsif.2011.0896
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