Cordycepin induces apoptosis by caveolin-1-mediated JNK regulation of Foxo3a in human lung adenocarcinoma

Forkhead transcription factor (Foxo3a) is a downstream effector of JNK-induced tumor suppression. However, it is not clear whether the caveolin-1 (CAV1)-mediated JNK/Foxo3a pathway is involved in cancer cell apoptosis. We found that cordycepin upregulates CAV1 expression, which was accompanied by JN...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Oncotarget
Hlavní autoři: Joo, Jong Cheon, Hwang, Jung Hoo, Jo, Eunbi, Kim, Young-Rang, Kim, Dae Joon, Lee, Kyung-Bok, Park, Soo Jung, Jang, Ik-Soon
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2017
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5355338/
https://ncbi.nlm.nih.gov/pubmed/28099944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.14661
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky